IGG is an open-source Java package with graphic interface to efficiently and consistently integrate genotypes across high throughput genotyping platforms (e.g., Affymetrix and Illumina), the HapMap genotype repository (http://www.hapmap.org/), and even genotypes from the collaborators¡¯ projects. It is equipped with a series of functions to control qualities of genotype integration and to flexibly export genotypes for genetic studies as well.
Very fast integration of whole-genome genotypes for poplular Affymetrix and Illumina DNA chips;
Ability to integrate whole-genome genotypes of TENS OF THOUSAND subjects by using less than 1.5 Gigabtye memory;
Integration of the latest unphased HapMap genotypes (including Phase III) and the PHASED genotypes;
Specical functional module to ease genotype IMPUTATION.
Comments and suggestions are welcome, please e-mail limx54@yahoo.com
Reference:
Li et al. (2007) IGG: A Tool to Integrate Gene chips for Genetic Studies. Bioinformatics 23(22):3105-3107. PubMedBioinformatics
Li et al. (2009) IGG3: a tool to rapidly integrate large genotype datasets for whole-genome imputation and individual-level meta-analysis. Bioinformatics 25(11):1449-50. PubMedBioinformatics
Miao-xin Li, Department of Biochemistry, The University of Hong Kong, All rights reserved.